Kayayyaki
Quercetin mai Soluble Ruwa don Babban Isar da Abinci
Quercetin Mai Soluble Ruwa: Haɓaka Samuwar Bioavailability da Majagaba Sabon Zaman Lafiya
Quercetin, wani fili na flavonoid da ake samu da yawa a cikin nau'ikan abinci na tsire-tsire irin su albasa, apples, da berries, ya daɗe yana zama maƙasudi a cikin binciken kimiyya da tattaunawa kan kiwon lafiya, godiya ga ƙarfinsa na antioxidant, anti-inflammatory, da sauran ayyukan nazarin halittu daban-daban. Duk da haka, rashin narkewar ruwa a zahiri yana kawo cikas sosai ga sha da amfani da shi a cikin jikin ɗan adam, ta haka yana iyakance cikakken fahimtar amfanin lafiyarsa. A cikin 'yan shekarun nan, tare da ci gaba da ci gaba a kimiyya da fasaha, quercetin mai narkewa mai ruwa ya fito, yana shawo kan kalubalen solubility na quercetin na gargajiya da kuma gabatar da nau'o'in aikace-aikace da fa'idodi na musamman.
Juya Halin Halitta: Cire Matsalolin Sha
quercetin na al'ada, saboda ƙarancin narkewar ruwa, yana gwagwarmayar narkewa a cikin gastrointestinal tract bayan an gudanar da baki, yana haifar da ƙarancin sha. Bincike ya nuna cewa yawan sha na hanji ya kusan kusan kashi 2%. Sabanin haka, quercetin mai narkewar ruwa yana yin amfani da fasahar yankan-baki, irin su fasahar nanomicelle da fasahar haɗa cyclodextrin, don haɓaka narkewar ruwa sosai. Misali, dakin gwaje-gwajen sabbin kayayyakin amfanin gona na Dryland na cibiyar binciken amfanin gona ta kudu, kwalejin kimiyyar aikin gona ta kasar Sin, ta yi nasarar shirya nanomicelles dauke da quercetin ta hanyoyin hada sinadaran. Wannan ƙirƙira ta inganta haɓakar ruwa na quercetin sosai, daidaiton hoto, da ingancin ɗaukar wayar salula. A sakamakon haka, quercetin na iya narkewa da kyau a cikin ruwan ciki, yana haɓaka wurin hulɗa da ƙwayoyin mucosal na hanji kuma yana haɓaka ingancinsa a cikin jikin ɗan adam. Nazarin da suka dace sun nuna cewa ana iya ƙara haɓakar quercetin mai narkewa da ruwa sau da yawa ko ma fiye da idan aka kwatanta da quercetin na gargajiya, yana ba da damar jiki don samun mafi kyawun sha da amfani da abubuwan da ke aiki na quercetin da cikakken buɗe tasirin sa na inganta lafiya.
Aikace-aikacen Lafiya Daban-daban
1. Tsarin Glucose na Jini
quercetin mai narkewar ruwa yana ba da sabon bege ga mutanen da suka damu game da lafiyar glucose na jini. Binciken da Cibiyar Nazarin 'Ya'yan itace ta Zhengzhou, Cibiyar Nazarin Kimiyyar Aikin Noma ta kasar Sin ta gudanar, ya nuna cewa quercetin, tare da sauran flavonoids na 'ya'yan itace, na iya hana ayyukan α-glucosidase tare. α-Glucosidase yana taka muhimmiyar rawa a cikin hydrolysis na carbohydrates, kuma hana ayyukansa na iya toshe narkewar abinci da sha na carbohydrates yadda yakamata, don haka yana taimakawa sarrafa matakan glucose na jini na postprandial. Tare da kyakkyawar solubility da ɗaukar nauyi, quercetin mai narkewa na ruwa zai iya shiga cikin ingantacciyar hanyar hana α-glucosidase, yana ba da tallafi mai ƙarfi don haɓaka samfuran aiki waɗanda ke da nufin daidaita glucose na jini na postprandial. Wannan yana da tasiri mai mahimmanci ga kula da lafiyar yau da kullun na masu ciwon sukari ko waɗanda ke da jujjuya matakan glucose na jini.
2. Kariyar Lafiyar Hanta
quercetin mai narkewar ruwa shima yana haskakawa wajen kiyaye lafiyar hanta. Wani bincike da tawagar farfesa Peng Cheng daga jami'ar Chengdu ta likitancin gargajiyar kasar Sin ta gudanar ya nuna cewa quercetin na iya inganta hanta mai kitse ta hanyar shiga tsakani wajen jujjuya makaman nukiliya na TFEB don rama rashin isassun autophagy. Ingantattun abubuwan sha na quercetin mai narkewa na ruwa yana ba shi damar isa hanta cikin sauri da inganci, yana ƙarfafa aikin autophagic na ƙwayoyin hanta, haɓaka metabolism na mai a cikin hanta, da sauƙaƙe kawar da abubuwa masu cutarwa. Wannan yana taimakawa wajen rigakafi da inganta cututtukan hanta daban-daban, irin su hanta mai kitse da cututtukan hanta na giya, ta hanyar rage barnar da barasa ke haifarwa da sauran abubuwan hanta.
3. Inganta Gyaran Gashi
Asarar gashi abin damuwa ne ga mutane da yawa, kuma quercetin mai narkewa da ruwa yana ba da sabon maganin wannan matsala. Wani bincike na hadin gwiwa da tawagar Farfesa Qu Jing daga cibiyar nazarin dabbobi, Cibiyar Kimiyya ta kasar Sin, ta gano cewa quercetin na iya inganta ci gaban gashi yadda ya kamata ta hanyar kunna hanyar HIF-1 a cikin sel endothelial na microenvironment. quercetin mai narkewar ruwa zai iya shiga cikin jini ba tare da matsala ba kuma ya isa yankin gashin gashi, yana yin cikakken tasirin sa akan microenvironment follicle gashin. Yana ƙarfafa bambance-bambance da yaɗuwar ƙwayoyin ƙwayar gashi, ta haka ne ke haɓaka haɓakar gashi. Ko asarar gashi ta haifar da damuwa, rashin daidaituwa na hormonal, ko wasu dalilai, quercetin mai narkewar ruwa yana ɗaukar alkawari a matsayin amintaccen magani mai inganci.
4. Inganta tsarin rigakafi
Quercetin kanta tana da wasu ayyukan rigakafi, kamar haɓaka kunna macrophage da ɓoye abubuwan da ke da alaƙa na rigakafi. Zuwan quercetin mai narkewa da ruwa yana ƙara haɓaka waɗannan fa'idodin. Kyakkyawan narkewar ruwan sa yana tabbatar da rarraba iri ɗaya a cikin jiki, yana ba shi damar yin aiki daidai da sassa daban-daban na tsarin rigakafi. Yana haɓaka aikin ƙwayoyin rigakafi kuma yana haɓaka ɓoyayyun abubuwan rigakafi kamar ƙwayar cuta necrosis factor-α da interferon-γ, yana taimakawa jiki mafi kyawun kariya daga ƙwayoyin cuta na waje kuma yana haɓaka rigakafi gabaɗaya. Wannan yana ƙarfafa mutane don samun juriya mai ƙarfi yayin fuskantar barazanar lafiya kamar ƙwayoyin cuta na mura da cututtukan ƙwayoyin cuta.
Bayanin Tsaro da Halayen Gaba
Shirye-shiryen quercetin mai narkewar ruwa galibi yana amfani da hanyoyin fasaha masu aminci da aminci, kamar fasahar nanomicelle da aka ambata a baya. Waɗannan hanyoyin suna inganta narkewar ruwa na quercetin ba tare da gabatar da sinadarai masu cutarwa ba, suna tabbatar da amincin samfurin. Bugu da ƙari, saboda haɓakar haɓakar halittunsa, ana buƙatar ƙaramin adadin quercetin don cimma fa'idodin kiwon lafiya iri ɗaya, yana ƙara rage haɗarin haɗarin haɗari masu haɗari.
Tare da ci gaba da zurfafa bincike da ci gaba da sabbin fasahohi, quercetin mai narkewar ruwa yana shirye don nuna ma fi girma yuwuwar aikace-aikacen a cikin abinci mai aiki, kayan abinci na abinci, kayan kwalliya, da masana'antar harhada magunguna. A cikin yanayin abinci mai aiki, ana iya haɗa shi cikin abubuwan sha da abubuwan ciye-ciye, yana ba masu amfani da kariya ta lafiya. A cikin masana'antar kayan shafawa, yin amfani da kayan aikin gyaran gashi da antioxidant, ana iya haɓaka samfuran da ke da ayyuka kamar asarar gashi da tsufa na fata. A fannin harhada magunguna, akwai babban alƙawari don ƙara bincika aikace-aikacensa wajen magance cututtuka masu tsanani da kuma taimakawa a fannin maganin ƙwayoyi, buɗe sabon hangen nesa don binciken likita da kiwon lafiya na gaba.
Magana
1.Cibiyar binciken amfanin gona ta kudu, Kwalejin Kimiyyar Noma ta kasar Sin. (nd). Sabbin Ci gaba a cikin Nano Dorewa-Sakin Kayayyakin Dauke da Magunguna. An dawo daga http://m.toutiao.com/group/7164215338974839308/?upstream_biz=doubao
2. Peng, C., da dai sauransu. (nd). Quercetin yana rage ethanol - haifar da steatosis na hanta a cikin ƙwayoyin L02 ta hanyar kunna fassarar TFEB don rama rashin isasshen autophagy. BINCIKEN PHYTOTHERAPY (Kashi na biyu a Kwalejin Kimiyyar Sinanci). An dawo da su daga bayanan ilimi
3. Qu, J., et al. (nd). Fassarar Tantanin halitta Guda Daya Yana Nuna Ƙarfafan Matsayin Quercetin wajen Inganta Farfaɗo Gashi. Protein & Kwayoyin. An dawo daga https://m.thepaper.cn/newsDetail_forward_21318679
4. Jin, Z., et al. (2024). Co - encapsulation na quercetin da resveratrol: Kwatanta a daban-daban yadudduka na zein - carboxymethyl cellulose nanoparticles. Jarida ta Duniya na Biological Macromolecules, 263, Mataki na ashirin da 127439. https://doi.org/10.1016/j.ijbiomac.2024.127439
5.Zhengzhou Cibiyar Nazarin 'ya'yan itace, Kwalejin Kimiyyar Aikin Noma ta kasar Sin. (2024). Flavonoids a cikin 'Ya'yan itãcen marmari Yana daidaita Glucose na Jini bayan Prandial. An dawo daga http://www.xinhuanet.com/science/20241105/c730eb7ee20a4e0ab8d2ec96570044ca/c.html
